Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Michael Thompson is a professor at McMaster University.

Kevin O’Donnell is R&D manager at DuPont Nutrition & Biosciences

Articles

Using a specific addition method to wet the powder bed in twin-screw granulation using a foam binder improves robustness for continuous solid-dosage drug product manufacturing.

Innovating Continuous Twin-Screw Granulation with Foam Delivery

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

RNA is easier to manipulate than DNA but challenging to deliver to the right cells.

Can RNA Simplify Gene Therapy Development?

EMA’s Committee for Human Medicinal Products (CHMP) has recommended that Kaftrio, a triple combination therapy for the treatment of cystic fibrosis, be authorized for marketing in the European Union. 

CHMP Recommends Marketing Authorization for Triple Combination Therapy for Cystic Fibrosis

The European Medicines Agency (EMA) has recommended a conditional marketing authorization be granted for Idefirix (imlinfidase) for the treatment of highly sensitized adult patients waiting for a kidney transplant.

EMA Recommends a Conditional Marketing Authorization for Kidney Transplant Medicine

The continuous manufacturing platform can be used for individual unit operations or a complete solid-dosage manufacturing line and can be integrated with third-party equipment.

GEA Aims to Expand Access to Continuous Manufacturing with ConsiGma 4.0

Full results from the Phase III ETHOS trial have demonstrated a statistically significant reduction in the rate of moderate or severe exacerbations in patients with moderate to very severe COPD after treatment with triple-combination therapy Breztri Aerosphere.

Phase III Trial Results Demonstrate Benefit of AstraZeneca’s Breztri Aerosphere

Inovio received a $71-million contract from the US Department of Defense to scale up manufacture of its Cellectra smart device to deliver its DNA vaccine.

Inovio to Scale-Up Manufacture of Intradermal Delivery Device for its COVID-19 Vaccine

Hallie Forcinio is packing editor for Pharmaceutical Technology and Pharmaceutical Technology Europe, editorhal@sbcglobal.net.

New options for pharmaceutical tubes enhance functionality, sustainability, and brand identity. 

Pharma Packaging Focus on Tubes

Citing clinical trial data that hydroxychloroquine did not show benefits for COVID-19 patients, FDA removes emergency use authorization for the drug as a treatment for the novel coronavirus. 

FDA Revokes EUA for Hydroxychloroquine

Novavax announces DoD contract to produce 10 million doses of COVID-19 vaccine candidate. 