Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Felicity Thomas is Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

Articles

Understanding formulation properties early in development can prevent some costly issues later on.


A Little Thought Goes a Long Way in Tableting

OSD forms are popular within the industry due to the various advantages they offer, but there are specific considerations required to get the best OSD form possible.


In Top Tablet Form

This article examines multi-tip tool technology for pharmaceutical tablet compression and the process control and validation issues that must be carefully evaluated to assess the potential for success. 

Considerations for Tablet Compression with Multi-Tip Tooling

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Tools help improve understanding of excipient risk in formulating OSD drugs.

Mitigating Risk in Formulating with Excipients

Understanding European GMPs and new rules from China for excipients are crucial for formulating solid-dosage drugs. 

Considering Excipient Regulations

Johnson & Johnson announces clinical trial plans for COVID-19 vaccine candidate, as well as plans to produce 1 billion vaccine doses. 

J&J Ramps Up COVID-19 Vaccine R&D

Synairgen, a respiratory drug discovery and development company, has announced that it has received expedited approvals to conduct a trial of its inhaled formulation of interferon-beta-1a, SNG001, in COVID-19 patients.


UK Company Starts Trials of Inhaled Formulation for COVID-19

Understanding of scale-up parameters and use of process analytical technology are important to meet demand for larger batch sizes.

Challenges in Clinical Manufacturing for Topical Drugs

Assays can provide a useful tool in determining the potential toxicity of drugs throughout the development cycle.


Keeping Toxicity to a Minimum

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Formulating fixed-dose combination drugs proves more complex than simply adding one ingredient to another. 