Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Rita Peters is the former editorial director of 

Pharmaceutical Technology, Pharmaceutical Technology Europe

Articles

Sharing know-how can help resolve common bio/pharma technical challenges.

Be a Part of the Solution

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Existing software tools cannot take into account the complexity of disease.

Can Artificial Intelligence Take the Next Step for Drug Repositioning?

Marc Brown, PhD, is chief scientific officer and co-founder of MedPharm.

Sarah Pratt is chief operating officer at MedPharm.

Christopher Harrison, is head of Process Development and Manufacture at MedPharm.

Using a QbD approach in the development and formulation of topical products will enable the drug developer to provide a robust control strategy for manufacturing.

QbD Strategies to Secure the Scale-Up of Semi-Solid Topical Formulations

Paul Kippax is product manager at Malvern Instruments.

Jennifer Burt is applications specialist at Malvern Panalytical.

Carolyn O'Grady is UK applications manager at Malvern Panalytical.

This article examines IVBE testing requirements for topical creams and explores some of the analytical techniques necessary. 

Testing Topicals: Analytical Strategies for the In-Vitro Demonstration of Bioequivalence

Jeff Williamson is director of Product Development at Lonza.

API-in-capsule approaches enable pharmaceutical companies to quickly assess new drug candidates with reduced API consumption and to increase speed to clinic.

Application of API-in-Capsule Best Practices to Accelerate Drug Product Development

Agnes Shanley is senior editor of Pharmaceutical Technology.

Sample preparation-specifically, API extraction and dilution-can introduce errors. Use of best practices and automation can reduce variability.

Ensuring Consistency in Content Uniformity Testing

Preliminary survey results rank the United States, Germany, and Japan as tier-one nations for bioprocessing performance and potential.

bioLIVE Survey Ranks Top Bioprocessing Nations

Drug product approval from FDA follows previous approvals from European and Japanese authorities.

FDA Approves Drug Product Manufacturing for Samsung BioLogics

Pharmaceutical companies are developing new strategies to address the ever-increasing development costs for new drug therapies and maximize the value of their existing drug portfolio.

Innovating Lifecycle Management with Data-Driven and Enabling Technologies

Sai V. Nudurupati is assistant director at AbbVie Inc. (North Chicago, IL)

Michael J. Kukulka is senior manager, Global Labeling, Regulatory Affairs, PRA Health Sciences (Deerfield, IL)

Takako Ono is principal scientist, Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Co. Ltd. (Osaka, Japan)

Haiyan Grady is associate scientific director CMCC, Takeda Development Center Americas, 300 Massachusetts Ave (4274), Cambridge, MA 02139, Tel: 1-224-554-2067, haiyan.grady@takeda.com

This article describes the approaches used during the development of a dexlansoprazole delayed-release orally disintegrating tablet (ODT) to evaluate tablet size and texture as they relate to disintegration rate and patient experience; in addition, the resistance to alcohol was also characterized. 