Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Agnes Shanley is senior editor of Pharmaceutical Technology.

Articles

Sample preparation-specifically, API extraction and dilution-can introduce errors. Use of best practices and automation can reduce variability.

Ensuring Consistency in Content Uniformity Testing

Preliminary survey results rank the United States, Germany, and Japan as tier-one nations for bioprocessing performance and potential.

bioLIVE Survey Ranks Top Bioprocessing Nations

Drug product approval from FDA follows previous approvals from European and Japanese authorities.

FDA Approves Drug Product Manufacturing for Samsung BioLogics

Pharmaceutical companies are developing new strategies to address the ever-increasing development costs for new drug therapies and maximize the value of their existing drug portfolio.

Innovating Lifecycle Management with Data-Driven and Enabling Technologies

Sai V. Nudurupati is assistant director at AbbVie Inc. (North Chicago, IL)

Michael J. Kukulka is senior manager, Global Labeling, Regulatory Affairs, PRA Health Sciences (Deerfield, IL)

Takako Ono is principal scientist, Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Co. Ltd. (Osaka, Japan)

Haiyan Grady is associate scientific director CMCC, Takeda Development Center Americas, 300 Massachusetts Ave (4274), Cambridge, MA 02139, Tel: 1-224-554-2067, haiyan.grady@takeda.com

This article describes the approaches used during the development of a dexlansoprazole delayed-release orally disintegrating tablet (ODT) to evaluate tablet size and texture as they relate to disintegration rate and patient experience; in addition, the resistance to alcohol was also characterized. 

Evaluation of Physical Characteristics of Dexlansoprazole Orally Disintegrating Tablets

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Jean-Yves Balfin, product manager at Korsch AG, speaks to Pharmaceutical Technology about the ins and outs of multilayer tableting. 

Key Considerations in Multilayer Tableting

Rita Peters is the former editorial director of 

Pharmaceutical Technology, Pharmaceutical Technology Europe

Frustrated by slow market adoption, Gottlieb maps out new plan for biosimilar competition.

FDA is Not Playing Games with Biosimilars

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Low-temperature chemistry enables performance of more challenging and selective chemistry.

Increasing API Complexity Drives Demand for Cryogenic Capabilities

Increasing dwell time can improve tablet production.

The Case for Extended Dwell Flat Tooling

Jeff Pavlovich is senior process safety engineer at Cambrex.

Determining how much containment is needed for API handling requires evaluation of multiple factors.