Development

Felicity Thomas is Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

Articles

Tight development timelines and accelerated approval pathways favor simple, cost-effective capsule formulations.

Capsule Innovations: Speeding Up Drug Development

Esra’a Albarahmieh is associate professor, Pharmaceutical Chemical Engineering department of the School of Applied Medical Sciences, German Jordanian University.

Mohammad Khanfar is associate professor, Pharmaceutical Chemical Engineering department of the School of Applied Medical Sciences, German Jordanian University.

Emad Alzubi is instructor and workshop manager at the Industrial Engineering department of the School of Applied Technical Sciences, German Jordanian University.

This study suggests that using a simple centrifugal method can produce a natural polymer-blend molecule that can successfully be used as an oral delivery mechanism for poorly soluble drugs. 

Fabrication Modulation of Zein-based Fibers for Oral Delivery of Hydrochlorothiazide

Gerry P. McNally is principal of McNally Consulting Group, LLC. With more than 25 years of experience, he earned a BS and PhD in chemistry from University College, Dublin, Ireland and holds more than 25 patents in drug delivery and formulation. He can be reached at gmcnally47@aol.com.

A quick look at the history of OTC dosage form development shows the importance of patient-centered innovation.


Oral Dosage Form Innovation in OTC Pharmaceuticals

The new molecules entering the development pipeline are bringing forth exciting challenges in drug delivery.

Delivering the Goods

Understanding formulation properties early in development can prevent some costly issues later on.


A Little Thought Goes a Long Way in Tableting

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Tools help improve understanding of excipient risk in formulating OSD drugs.

Mitigating Risk in Formulating with Excipients

Understanding European GMPs and new rules from China for excipients are crucial for formulating solid-dosage drugs. 

Considering Excipient Regulations

Donald A. Johnson, PhD, RAC is senior scientific advisor at Eurofins BioPharma Product Testing.

This paper discusses what causes cross-linking, how cross-linking is addressed with addition of enzymes, and consideration for occasional high results that can be obtained during release testing.

Quantitative Rupture Testing of Soft Gelatin Capsules: Understanding Aberrant Results

The aim of this study was to prepare taste-masked drug-resin complex using ion exchange resin Kyron T-134.

Development of Taste-Masked Oral Reconstitutable Suspension of Cetirizine Dihydrochloride

Spray drying is a versatile and rapid technique that can provide companies with a suitable and scalable option to improve the solubility and bioavailability of drug products.


Formulation and Drug Delivery, Solid Dosage