Development

Gayatri C.Patel, M.Pharm, PhD, is associate professor in the Department of Pharmaceutics & Pharmaceutical Technology, Ramanbhai Patel College of Pharmacy at the Charotar University of Science and Technology, Changa Campus, Changa- 388 421, Anand, Gujarat, India, gayatripatel.ph@charusat.ac.in, +91 2697 265162.

Articles

Research examined the effects of varying excipient and polymer weight in coatings designed to optimize the release of diclofenac sodium. The goal was to release it at night to improve the treatment of rheumatoid arthritis. 


Optimizing Compression Coating for Pulsatile Release Tablets

CPI, the University of Strathclyde, GSK, and AstraZeneca Collaborate on a continuous direct compression digital twin for pharmaceutical formulation optimization. 

UK Collaboration Uses a Direct Compression Digital Twin to Speed OSD Formulation

Frank Romanski, PhD is head of Global Marketing, Pharma Solutions, BASF Corp, Florham Park, NJ, frank.romanski@basf.com.

High-throughput platforms can be used to develop tertiary phase diagrams, which can be leveraged to identify the most stable SEDDS formulations and excipients for lipid-based drug delivery systems.

How Excipient Type Influences Self-Emulsifying Drug Delivery

FDA has approved Novo Nordisk’s Rybelsus (semaglutide), a glucagon-like peptide receptor protein treatment in oral tablet form for type 2 diabetes.

FDA Approves First Oral GLP-1 Treatment for Type 2 Diabetes

The European Medicines Agency’s Committee for Medicinal Products for Human Use has recommended the approval of AstraZeneca’s Qtrilmet (metformin hydrochloride, saxagliptin, and dapagliflozin) modified-release tablets for treating type-2 diabetes.

AstraZeneca’s Combination Diabetes Pill Recommended for Approval in EU

Felicity Thomas is Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

In this interview, the main uses and benefits of NIR spectroscopy in tableting are discussed.


Putting NIR to Good Use in Tablet Formulation and Manufacture

Under an agreement, Colorcon will incorporate TruTag’s edible microtag technology in its coatings.

Colorcon, TruTag Team Up On-Dose Authentication

Several trends are driving change in oral solid‑dosage forms and giving rise to the requirement of ‘fit-for-purpose’ excipients.


Selecting a Solid Approach

Flexibility and well considered manufacturing approaches could help tablet manufacturers face the increasing pressure resulting from the shifting bio/pharma development landscape.


Under Pressure

Kelly Boyer is general manager, Film Coatings at Colorcon Inc.

Market demand and regulatory guidance continues to promote improved medication design.


Formulation and Drug Delivery, Solid Dosage