Drug Development

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Articles

Advances in chemical synthesis are enabling greener, more cost-efficient processes for API manufacturing.

Catalysis, Flow Chemistry Impact API Manufacturing

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Transdermal and inhaled/nasal delivery provide alternative routes of administration for macromolecules.

Alternative Routes for Delivering Macromolecules

A new study from the United States National Institutes of Health (NIH) found that pairing the antidepressant amitriptyline with drugs designed to treat central nervous system diseases, enhances drug delivery to the brain by inhibiting the blood-brain barrier in rats. The blood-brain barrier serves as a natural, protective boundary, preventing most drugs from entering the brain. The research, performed in rats, appeared online April 27, 2017 in the Journal of Cerebral Blood Flow and Metabolism.

NIH Study Shows Antidepressants May Enhance Drug Delivery to Brain

Catalent combines its formulation expertise, manufacturing excellence and particle size reduction technologies to provide a broad range of solutions in the development of inhalation and nasal drug products.

Manufacturing and Formulation Solutions for Inhaled Dose Forms

Companies believe that biologics and biosimilars would experience the fastest growth over the next year; there is also interest on increasing market penetration of generic drugs.

Growth of Japanese Pharma Market Driven by Biologics and Generic Drugs, Says CPhI Report

Sandoz, a Novartis division, announced  that the Committee for Medicinal Products for Human Use (CHMP) has adopted positive opinions recommending the approval of its biosimilars rituximab and  etanercept in Europe, for the same indications as the respective reference medicines.

Sandoz’s Rituximab and Etanercept Biosimilars Recommended for European Approval

In implementing quality by design for drug formulation, it is crucial to identify the critical properties of excipients and understand how their variation affects the final drug product.

Understanding How Excipients Affect Drug Quality

The funding allows the company to broaden its range of services and finance its move to new laboratory facilities in the Illkirch-Graffenstaden innovation park in northeast France.

Inoviem Scientific Secures Funding to Finance Expansion

Caroline Hroncich was associate editor for Pharmaceutical Technology, Pharmaceutical Technology Europe, and BioPharm International from 2015 to 2017.

Pharmaceutical Technology spoke with CPhI North America presenter Jonathan Helfgott to discuss navigating GDUFA and helpful tips for submitting successful ANDAs.

Former CDER OSI Associate Director for Risk Science to Speak at CPhI North America 2017

The project will foster the translation of nanomedicine applications for the treatment of cardiovascular diseases.

Formulation and Drug Delivery