Drug Development

Articles

A recent FDA guidance places greater attention on cocrystals as a tool in solid-dosage formulation.

Examining the Role of Cocrystals in Drug Development and Manufacturing

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

Industry experts share perspectives on risk assessment and mitigation in excipient manufacture and the excipient supply chain.

Risk Assessment of Excipients

A simple, rapid analytical method for the determination of palladium in pharmaceutical production samples will speed up development and optimization of reactions involving palladium catalysts.

Merck/PITT Collaboration Demonstrates Rapid Method for Evaluation of Residual Palladium

Stapled peptides offer promise to enable cell permeability, binding to therapeutic targets, and modulation of biological pathways.

Advancing Peptide Synthesis Through Stapled Peptides

View companies' outsourcing profiles from PharmTech's 2013 Outsourcing Resources Fast Locator Index in the following categories.

Fast Locator 2013-2014 Index

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Rx-360, a pharmaceutical industry supply-chain consortium, is advancing approaches between pharmaceutical companies, suppliers, and contract manufacturers to better secure the pharmaceutical supply chain.

Rx-360 Advances Supply-Chain Security

Industry groups offered perspectives on the strengths and weaknesses of the European Falsified Medicines Directive.

Implications for APIs in the European Falsified Medicines Directive

External manufacturing plays a crucial role in pharmaceutical companies’ supply strategy. The author examines market trends for the captive and merchant global market for active pharmaceutical ingredients and intermediates.

A Shifting Landscape for the Global API Market

Novel, atom-efficient routes to amides from esters and carboxylic acids for more sustainable manufacturing.

Reducing the Complexity of Commercial-Scale Amide Formation

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

New routes enable the efficient synthesis of enantiopure sulfinamides and structurally and sterically diverse P-chiral phosphine oxides.

Ingredients