Development

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Articles

Because peptoids are relatively easy to synthesize, have tremendous sequence diversity, and are more proteolytically stable than peptides and proteins, they have significant potential for use as APIs, drug-delivery agents, and in numerous biomedical applications.

The Promise of Peptoids

Access to simpler and more direct methodologies for the incorporation of fluorinated substituents remains an unmet need in pharmaceutical synthesis. An analysis of recent trends in fluorination chemistry.

Developing New Reagents for Advanced Fluorination Chemistry

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

Continuous flow chemistry offers potential for greater control, improved safety and environmental profiles, and efficient chemical transformations.

Advancing Flow Chemistry in API Manufacturing

Contract API manufacturers proceed with select investment in capacity and service additions.

Fine-Chemical Producers Make Targeted Investments

As the strategic value of emerging markets increase, pharmaceutical companies increase their R&D and manufacturing investments.

Navigating the Global Manufacturing Supply Chain

FDA's requirements for API manufacturers in regards to ICH Q7.

Adhering to ICH Q7 for GMPs

Visual mapping can provide a particle-size distribution estimate.

Measuring API Particle Size Distribution

Eric Langer has over 25 years experience in biotechnology and life sciences strategic marketing management, market research, and publishing. He has held senior management and marketing positions at biopharmaceutical supply companies. He has published and authored many books and reports on topics in Biotechnology, Large-scale BioManufacturing, and bioscience commercialization and communication. He teaches at Johns Hopkins University marketing management, biotech marketing, services marketing, and marketing in a regulated environment. In 1989 he co-founded BioPlan Associates, Inc. to provide market analysis, and strategy to biotech and healthcare organizations.

Growth is seen in outsourcing of insect- and plant-cell-based bioproduction expression systems.

Outsourcing Nontraditional Protein Expression Systems

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Pharmaceutical Technology brought together a panel of industry experts for a special forum to discuss solubilizing polymers and the related formulation strategies for poorly soluble drugs.

Advancing Polymers for Solubility Enhancement

Factors for assessing excipient variability, the associated challenges developers need to address to design and manufacture solid oral drug products, and solutions for such challenges are examined.

Ingredients