Drug Development

Articles

Ionic liquids provide an alternative to certain solvents in select reactions used to synthesize intermediates and active pharmaceutical ingredients.

Ionic Liquids in the Chemical Synthesis of Pharmaceuticals

The potent nature of HPAPIs means there must be careful evaluation of the compound for its level of toxicity when considering manufacture.

Let's talk the same language

Also, Zentiva accepts Sanofi's increased takeover bid, Oriel Therapeutics appoints Richard Fuller CEO, more...

Company and People Notes: Committee on Energy and Commerce Expands Ranbaxy Probe; Eli Lilly Appoints John C. Lechleiter Chairman of the Board; More...

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The biopharmaceutical company ImClone Systems rejected Bristol-Myers Squibb's previously announced bid of $60 per share in cash or $4.5 billion for acquiring ImClone, citing the bid as "inadequate."

ImClone Systems Rejects Bid by Bristol-Myers Squibb

Also, Quintiles to expand Singapore operations; Christine A. Poon, chairman of Johnson & Johnson's pharmaceuticals group, to retire; more...

Company and People Notes: King Commences Tender Offer for Alpharma; Genentech Appoints Morgan Sheng VP of Neuroscience; More...

The European Chemical Industry Council and five national chemical associations representing France, Germany, Italy, Spain, and the United Kingdom, have launched ReachLink. ReachLink is a company founded to help companies participate in the Substance Information Exchange Forum (SIEF), which is designed as an information-sharing vehicle to facilitate companies in meeting requirements under REACH

CEFIC Forms REACH Service

Also, Human Genome Sciences enters pact with Hospira, Zosano Pharma names Gail Schulze chair and CEO, more...

Company and People Notes: FTC Asks Teva and Barr For Additional Information, GSK's Chris Viehbacher to Leave Company, More...

Boehringer Ingelheim and and Hisoar (Taizhou, China), a pharmaceutical production company, formed a strategic production alliance in China.

Boehringer Ingelheim Partners with Chinese Intermediates Producer

Also, Novartis stops development on "Aurograb," Zealand Pharma appoints David H. Solomon as CEO, more...

Company and People Notes: GSK and Valeant Collaborate on Investigational Drug, Aptuit Appoints Timothy C. Tyson Executive Chairman and Acting CEO, More...

The pharmaceutical majors deploy green-chemistry strategies to improve the synthesis of active pharmaceutical ingredients and intermediates.

Ingredients