Manufacturing

Anna Novikova, PhD, is a process analytical technology scientist at Fette Compacting, anovikova@fette-compacting.com.

Articles

At-line NIR measurements can replace a laboratory HPLC measurement for API content in oral solid-dosage drug manufacturing.

The Road to Real-Time Release: At-line NIR Testing

Agnes Shanley is senior editor of Pharmaceutical Technology.

Early adopters of continuous manufacturing approaches shared their plans and some of their experiences at the 11th annual Charles Jarowski Symposium in Industrial Pharmacy.

Industry Experiences in Continuous Manufacturing for Encapsulation and Tableting

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

A presentation at the Leistritz Pharmaceutical-Nutraceutical Extrusion Seminar explained how simulation tools benefit the development process.

Simulating the Pharma Twin-Screw Extrusion Process

Although continuous approaches offer significant benefits for some products and processes, batch manufacturing is not going away any time soon.

Continuous Manufacturing: Addressing the Tough Questions

Continuous manufacturing may offer huge opportunities, but it will not be right for
every facility or product.


Batch or Continuous? Ask the Right Questions During Scale Up

The UK’s Centre for Process Innovation is collaborating with partners GSK and AstraZeneca to establish a continuous wet granulation manufacturing facility for small-scale development of oral solid-dosage pharmaceuticals.

CPI Builds Open Innovation Facility for Continuous Wet Granulation

Educational sessions on the INTERPHEX show floor will include a panel discussion on implementing continuous manufacturing.

INTERPHEX 2019 Keynote Series Presents Panel Discussion on OSD Continuous Manufacturing

In OSD continuous manufacturing, flexible batch sizes can optimize supply, but equipment and processing challenges are still being addressed. 

OSD Continuous Manufacturing Strategies

FDA guidance on quality considerations for continuous manufacturing should help advance implementation by providing clarity and giving companies more confidence to make investments in the new technology.

FDA Issues Draft Guidance on OSD Continuous Manufacturing

The RK-1 continuous mixing processor from Readco Kurimoto is suited for testing formulations in continuous processing conditions.

Manufacturing, Continuous Solid Dosage Processing