Manufacturing

Articles

Tornado Spectral Systems, winner of the 2018 CPhI Excellence in Pharma Award for Analysis, Testing, and Quality Control, discusses real-time process measurement for biopharmaceutical and small-molecule drug manufacturing. 

Raman Spectroscopy System Allows On-line Process Measurement

Susan Haigney is lead editor of Pharmaceutical Technology and Pharmaceutical Technology Europe.

Shortages of life-saving drugs are a regulatory and industry concern. Proper process development may help to ensure drug supply.

Proper Process Development and Drug Shortages

Sean Bermingham is head of Formulated Products at Process Systems Enterprise, Ltd., 26-28 Hammersmith Grove, Hammersmith, London, UK, s.bermingham@psenterprise.com

Dana Barrasso is senior consultant at Process Systems Enterprise, Inc., 3 Wing Drive, Cedar Knolls, NJ, d.barrasso@psenterprise.com. 

Mechanistic process and product modeling turns data into knowledge that can be extrapolated with known confidence for design space characterization and risk assessment.

Design Space Characterization and Risk Assessment Through Mechanistic Modeling

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

A twin-screw extruder can be used as a continuous wet granulator.

Considering Twin-Screw Granulation

Coperion’s ZSK 18 MEGAlab extruder fulfills requirements for both wet extrusion and hot-melt extrusion pharmaceutical processes.

Extruder for Continuous Pharma Processes Performs in R&D and Small-Scale Production

A twin-screw extruder can be used as a continuous wet granulator or as a continuous mixer for a wet gelatin mass. 

Considering Twin-Screw Extruders for Continuous Mixing and Granulation

The new industry-led Medicines Manufacturing Innovation Center (MMIC) will offer a unique service to develop and implement novel manufacturing techniques.

New Innovation Center in Scotland Aims to Revolutionize Medicines Manufacturing

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

From separation systems to reactor technology, new tools are increasing the feasibility of continuous API production.

New Tools Outline Advances for Continuous API Processing

The UK’s University of Sheffield opened a new chemical engineering teaching plant for continuous oral solid-dosage pharmaceuticals using GEA’s multipurpose platform.

University of Sheffield Opens Continuous OSD Pilot Plant

GEA and Perceptive Engineering will collaborate to promote and deploy multivariate monitoring and advanced process control (APC) solutions for batch and continuous pharmaceutical process units.

Manufacturing, Continuous Solid Dosage Processing