Manufacturing, Expression Systems

Cobra Biologics Expands Gene Therapy Manufacturing Operations

April 18, 2017

PTSM: Pharmaceutical Technology Sourcing and Management

Cobra will increase capacity in response to customer demand for DNA and viral vector production.

Sartorius Stedim Biotech Introduces Fully Integrated Upstream Platform

September 01, 2016

The platform combines an expression system with equipment and process controls to enable rapid development and scale-up of robust titers.

Alnylam Moves Forward on Multi-Product RNAi Facility

August 04, 2016

Jacobs Engineering Group was awarded a contract to provide engineering services and procurement for Alnylam Pharmaceuticals’ new manufacturing facility in Norton, Massachusetts.

AstraZeneca Begins Phase I Testing of its RNA-Based Therapeutic with Moderna

July 26, 2016

The therapeutic candidate AZD8601is an investigational mRNA-based therapy that will be tested for its ability to regulate the protein that influences vascular tissue growth.

Ionis Pharmaceuticals Licenses Oral RNA-based Therapeutic to Janssen

July 19, 2016

The antisense drug will be the first in the companies’ joint development deal for medications to treat autoimmune disorders of the gastrointestinal tract.

Using a New CRISPR Effector to Edit RNA

June 02, 2016

As the battle for ownership over the use of CRISPR to edit DNA heats up, some of the CRISPR pioneers refocus their efforts to demonstrate the technology’s applications for editing RNA.

AstraZeneca Partners with WCPR to Research Secretome

December 11, 2015

AstraZeneca partners with the Wallenberg Center for Protein Research to conduct studies on the Secretome.

Abenza Acquires US CDMO PacificGMP

September 14, 2015

Abenza acquired biopharmaceutical CDMO PacificGMP and expanded the company’s San Diego facility.

Medimmune and Inovio Pharmaceuticals Form Cancer Pact

August 10, 2015

Deal includes rights to Inovio’s INO-3112 HPV cancer vaccine and preclinical collaboration to develop additional cancer vaccine candidates.

Using mAbs to Access Undruggable Targets

June 22, 2015

Monoclonal antibodies can facilitate the entry of radiopharmaceuticals into cells, David Scheinberg said at BIO 2015.