Manufacturing

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Articles

Boehringer Ingelheim has entered into a non-exclusive technology and commercial license option agreement with BaroFold. Under the terms of the agreement, Boehringer Ingelheim will license BaroFold's pressure-enabled manufacturing technology (PreEMT).

Boehringer Ingelheim Licenses BaroFold's PreEMT High-Pressure Protein-Refolding Technology

A Technical Forum Moderated by Patricia Van Arnum, featuring contributions from PerkinElmer, BioTools, Chiral Technologies, Shimadzu Scientific Instruments, GE Analytical Instruments, and Waters.

Analytical Applications

The authors investigate the effect of low pH and ionic strength on aggregation using turbidity measurements and size-exclusion–high-performance liquid chromatography.

Protein Sensitivity to Tungsten

Could oral absorption-enhancing technologies change the shape of protein delivery?

Reformulating Injectables for Oral Delivery

New product reviews for October 2011 focusing on analytical instrumentation.

In the Spotlight October 2011

The authors present a method for controlling the release of therapeutics by applying a plasma polymer layer to the surface of porous materials.

Controlled Release from Porous Platforms

Two popular methods for detecting protein aggregates are analytical ultracentrifugation (AUC) and size-exclusion chromatography?multiangle light scattering (SEC?MALS). These techniques? results correlate relatively well, but each one has its own strengths.

Analyzing Aggregate-Detection Methods

The author describes the development of small-angle X-ray scattering and analyzes its advantages in the characterization of drug-delivery systems and large molecules. This article is part of a special Analytical Technology issue.

Small-Angle X-ray Scattering for Pharmaceutical Applications

Duke University researchers have found a possible alternative to lyophilization.

A Glass Act

Sanjay Garg, PhD, is an associate professor at the School of Pharmacy, University of Auckland, Auckland, New Zealand, and a member of the Pharmaceutical Technology Editorial Advisory Board.

A timely new book explains techniques for conformational analysis.

Manufacturing, Expression Systems