Manufacturing

Michelle Hoffman, editorial director of Pharmaceutical Technology.

Articles

The second annual Pharmaceutical Technology Bioprocessing Survey offers a snapshot of the industry following 2009's megamergers.

Trends in Bioprocessing

Pharmaceutical Technology talked to drugmakers, equipment vendors, and service providers to learn more about the advantages and disadvantages of rapid microbial-detection methods.

An Overview of Rapid Microbial-Detection Methods

The authors sought to improve the productivity of protein synthesis by using a highly active cell-free extract from Escherichia coli and by optimizing buffer conditions and shaking conditions.

Large-Scale Protein Production with a Cell-Free System

A recent book reminds readers that small-molecule chemistry has enabled advances in biotechnology.

Whatever Happened to Classical Chemistry?

The author describes how Merrion Pharmaceuticals reformulates parenteral drugs into tablets and capsules that are easier for patients to take and provide better bioavailability.

From Needle to Pill: Reformulating Injectable Drugs for Oral Delivery

The author of a book about biopharmaceutical production includes irrelevant information.

More Than You Need to Know about Manufacturing Pharmaceutical Proteins

Formulators and manufacturers have many options for modifying release profiles in multiple-API products.

Down the Track: Different Speeds with Multiple APIs

A Pharmaceutical Technology report looks at trends in biopharmaceutical manufacturing. This article contains bonus online-exclusive material.

The Biopharmaceutical Manufacturing Survey

The emergence of influenza A (H1N1) and the efforts to provide vaccines to the vulnerable are timely examples of biopharmaceuticals' continuing importance.

Could We Make Large Molecules with Less Labor?

The authors describe a novel analytical approach that uses the shape-analysis capabilities of MFI to detect and enumerate silicone oil microdroplets in protein formulations that also contain aggregates of similar size and in a similar concentration.

Manufacturing, Expression Systems