Dosage Forms

Johannes G. Khinast is professor at the Institute of Process and Particle Engineering, Graz University of Technology, Austria

Josef Lingitz is project manager, M&R Automation GmbH, Graz, Austria.

Sharareh Salar-Behzadi is principal scientist atResearch Center Pharmaceutical Engineering (RCPE)GmbH, Graz, Austria.

Stephan Sacher is senior scientist at the Research Center for Pharmaceutical Engineering GmbH in Graz, Austria.

Articles

This novel technology was developed in response to challenges involved in conventional manufacturing of multilayer tablets, including in-line control of the tablet weight, the tendency to delamination, direct contact between the two tablet layers, and cross contamination.

Gluing Pills Technology for the Production of Multi-Layer Tablets

Lawrence H. Block, PhD, is a professor of pharmaceutics at the School of Pharmacy, Duquesne University, Pittsburgh, PA 15282, tel. 412.396.6362, fax 412.396.5599, block@duq.edu.

Catherine Sheehan is the director for the excipients group at the United States Pharmacopeia in Rockville, Maryland.

This article summarizes the evolution of the viscosity standards and their corresponding applications in the USP−NF compendia.

Characterization of Polymeric Excipients

Smruti P. Chaudhari, PhD, is a development scientist at Metrics Contract Services.

A case study reviews the reformulation and scale up of high drug load prototype using wet granulation process for a model formulation.

Wet Granulation Resolves Tablet Reformulation Challenges

Manufacturing will be carried out at the Pfizer Newbridge, Ireland, facility, which is now part of Pfizer CentreOne’s contract manufacturing network.

CMO Pfizer CentreOne Adds Highly Potent Solid Oral Dose to Portfolio

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Improved process analytical technology and new ways of thinking seek to enhance measurement and control for next-generation pharmaceutical manufacturing.

Overcoming Obstacles in Process Analytical Technology

Soft sensors are powerful tools that can be used along with spectroscopic instruments in on-line measurement.

Using Spectroscopic and Virtual Sensor PAT in Continuous Solid-Dosage Manufacturing

Pramote Cholayudth previously was the managing director of the Professional Conference Center, Ltd. He currently is a validation consultant to Biolab Co., Ltd., in Thailand. He is the founder and manager of PM consult, cpramote2000@yahoo.com.

This article introduces the concepts of pooled variance and the central limit theorem, which are intended for establishing acceptance criteria for blend uniformity data of granular powder blends when a significant degree of sampling bias is involved.

Establishing Blend Uniformity Acceptance Criteria for Oral Solid-Dosage Forms

Camfil Air Pollution Control has expanded its testing laboratory and added a dust collection test rig for the ANSI dust collection standard.

Camfil APC Expands Laboratory for Testing Dust Collection Systems

GEA’s ConsiGma continuous tableting line combined with Siemens’ automation and Sipat data management systems enables continuous manufacturing.

Siemens and GEA Partner to Deliver Solid-Dosage Continuous Manufacturing

Catalent announces a development agreement with JOT to evaluate softgel options for a resveratrol drug candidate.

Solid/Semi-Solid Dosage