Dosage Forms

Johan Remmelgas is associate principal scientist, manufacturability, Pharmaceutical Technology & Development, AstraZeneca R&D, Gothenburg, Sweden.

Articles

Moisture uptake during the end-to-end manufacturing process and supply chain can affect product quality. Simulation tools based on mechanistic models help define storage and handling requirements for oral solid-dosage drugs.

Predicting Moisture Uptake in Solid Dosage Packaging

Hallie Forcinio is packing editor for Pharmaceutical Technology and Pharmaceutical Technology Europe, editorhal@sbcglobal.net.

Advances in materials and equipment for pharmaceutical blister packaging protect quality and enhance shelf life.

Blister Packaging Moves Forward

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Principles of dissolution testing, including method development and testing apparatus, are reviewed.

Factors to Consider in Dissolution Testing

FDA and BARDA awarded a contract to Continuus Pharmaceuticals to develop an end-to-end continuous manufacturing process for solid-dosage drugs.

Continuus Pharmaceuticals Partners with FDA and BARDA

Martin KÃ¶berle, PhD, is head of Analytical Development &Stability Testing, at Hermes Pharma.

Detlev Haack, PhD, is head of Research & Development at Hermes Pharma.

Hot-melt coating was used to develop taste-masked orally disintegrating granules of acetaminophen and caffeine.

From Bitter to Sweet: Developing a User-Friendly Painkiller

Catalent adds two softgel facilities and packaging capabilities with acquisition of Canada-based Accucaps.

Catalent Expands Softgel Capacity with Accucaps Acquisition

Elizabeth Rivera is a technical services manager at the Life Sciences Division of STERIS Corporation.

Paul Lopolito is a technical services specialist at STERIS, Mentor, OH.

A lifecycle approach can be used to develop GMP-compliant cleaning procedures for continuous manufacturing of solid-dosage pharmaceuticals.

Cleaning Validation in Continuous Manufacturing

Fernando J. Muzzio, PhD, is a professor and the director of the pharmaceutical engineering program at the Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854-8058, tel. 732.445.3357.

C-SOPS, Department of Chemical and Biochemical Engineering at Rutgers, The State University of New Jersey

Shear-sensitive ingredients in a tableting formulation experience different conditions in a batch tumble blender than they would in a continuous paddle blender.

Lubrication in Continuous Tubular Powder Blenders

A dissolution method should have adequate discriminatory power to detect formulation changes that affect the dissolution rate of a drug product.

Dissolution Testing

Sharon Nowak is Global Business Development Manager for the food and pharmaceutical industries, K-Tron (Schweiz) AG.

Designing loss-in-weight feeders for accurate and consistent refill is crucial to a continuous solid-dosage process.

Solid/Semi-Solid Dosage