Dosage Forms

Articles

This study examines the effect and interaction of variations in hypromellose physicochemical properties.

Applying Quality by Design for Extended Release Hydrophilic Matrix Tablets

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The physical form of an API is an important consideration in formulation development. Particle-engineering technologies, such as crystal design for controlling crystallisation and producing cocrystals, particle-size reduction and amorphous solid dispersions, help to optimise delivery of a drug.

Seeking Solutions in Solid-State Chemistry

Andreas Gryczke is the technical marketing manager of technology commercialization at Evonik RÃ¶hm GmbH.

The advantages and disadvantages of hot-melt extrusion in solid dispersion formulations.

Solid Dispersions by Hot-Melt Extrusion

The authors investigate the tablet-coating process using a combination of different simulation techniques.

Peer Reviewed: Numerical Simulation of Tablet Coating

The authors describe a solid form technology platform used to optimize salt selection, cocrystallization identification and modification, or the development of a free form.

Developing the Optimal Solid Form

Rob Blanchard and Clive Roberts discuss the issues surrounding tablet sticking.

Tackling Tablet Sticking

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Industry experts share their insight on solid-dosage and sterile manufacturing.

35th Anniversary Special: Breakthroughs and Emerging Technologies in Manufacturing

Developments in hot-melt extrusion using twin-screw extruders to make solid-dosage drug forms.

Hot-Melt Developments

In addition to the established coating systems (like the BFC and the BFC TriPan), Bohle developed a new coater to face the market needs, the Bohle-Tablet-Coater BTC.

The Bohle-Tablet-Coater BTC

New coating technologies achieve high uniformity and reduce waste through mixing system advances and pan and airflow configuration.

Solid/Semi-Solid Dosage