Dosage Forms

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Articles

Advances in process analytical technology and in defining lots for release are key for enabling use of continuous processes in solid-dosage manufacturing.

Ongoing Challenges in Continuous Manufacturing

Stephanie Sutton was an assistant editor at Pharmaceutical Technology Europe.

A technical forum featuring Tim Freeman of Freeman Technology and Carl Levoguer of Malvern Instruments.

Optimizing Tableting Processes with Quality by Design

As part of an ongoing collaboration into tabletting science, I Holland and the UK's University of Nottingham have launched a two-year programme to investigate the cause of tabletting sticking.

Research Project Targets Tablet Sticking

In our tablet coating process, we are losing up to 15% of our coating solution in each processing run. What can we do to prevent this problem in order to reduce waste and increase our cost efficiency?

Reducing Waste in Tablet Coating

CML - Solid State Chemistry

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The article examines some recent developments for this process step and for continuous manufacturing overall.

Advancing Unit Operations for Continuous Processing in Solid-Dosage Manufacturing

Tim Freeman is Managing Director of powder characterization company Freeman Technology for whom he has worked since the late 1990s. He was instrumental in the original design and continuing development of the FT4 Powder RheometerÂ® and through his work with various professional bodies, and involvement in industry initiatives, is an established contributor to wider developments in powder processing.Tim has a degree in Mechatronics from the University of Sussex in the UK. He is a mentor on a number of project groups for the Engineering Research Center for Structured Organic Particulate Systems in the US and a frequent contributor to industry conferences in the area of powder characterisation and processing. A past Chair of the American Association of Pharmaceutical Scientists (AAPS) Process Analytical Technology Focus Group Tim is a member of the Editorial Advisory Board of Pharmaceutical Technology and features on the Industry Expert Panel in European Pharmaceutical Review magazine. Tim is also a committee member of the Particle Technology Special Interest Group at the Institute of Chemical Engineers, Vice-Chair of the D18.24 sub-committee on the Characterization and Handling of Powders and Bulk Solids at ASTM and a member of the United States Pharmacopeial (USP) General Chapters Physical Analysis Expert Committee (GC-PA EC).

This article considers the different conditions to which the powder is subjected in the tableting process, and discusses which powder properties should be measured to accurately reflect likely powder behavior in the process.

Powder Testing Techniques for Tablet Manufacture

Taste-masking is an important consideration to ensure patient compliance.

Advances in Taste-masking

Experts in solid dosage discuss the formulation and manufacture of multilayer tablets.

Multilayer Tablets: Key Challenges and Trends

Angie Drakulich was editorial director of Pharmaceutical Technology.

FDA answers key questions about the October 2011 guidance on using physical–chemical identifiers in solid oral dosage products to help prevent and avoid counterfeiting.

Solid/Semi-Solid Dosage