Topic

Articles

A rheometer and powder flow tester can measure how pharmaceutical materials, such as powders from a hopper, flow.

Understanding the Flow Behavior of Materials

Multi-faceted powder characterization, including measurement of dynamic properties, can be used to correlate powder properties and process performance to support equipment selection, optimization, and troubleshooting.

Identifying Powder Properties that Define Process Performance

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Appropriate cleaning procedures are crucial for any cGMP aseptic or sterile pharmaceutical manufacturing process, including vial filling; operators share best practices for cleaning.

Best Practices for Cleaning a Filling Line

Operator attention to detail and adherence to procedures are crucial for proper cleaning.

Cleaning a Vial Filling Line

Paperless operations improve efficiency and increase assurance of product quality.

Implementing Electronic Production Records

Experts discuss crucial aspects of measuring the stability of biologics, which exhibit greater variability in stability testing than do small-molecule drugs.

Best Practices for Stability Testing of Biologics

Biologics exhibit greater variability in stability testing than do small-molecule drugs, and maintaining a stable test environment is crucial.

Testing the Stability of Biologics

Careful choice of wash-water parameters and attention to water quality and basket loading are important for optimal cleaning.

Troubleshooting