Targeting Nitrosamine Precursors with Novel Active Material Science Scavenger Technologies

Join this webinar to explore how the latest innovations in active material science technologies can mitigate N-nitrosamine risks by addressing the root cause of nitrosamine formation. Learn how customizable active packaging solutions can be tailored to suit specific drug requirements, enabling pharma developers to meet regulatory compliance and mitigate risk without requiring extensive formulation changes or disruption to manufacturing workflows.

Register Free: https://www.pharmtech.com/pt_w/scavenger-technologies

Event Overview:

As pharma companies face increasing regulatory scrutiny and risk of product recalls due to N-nitrosamine formation in drug products, the mechanism of reaction and root cause of formation is not always understood, which can make risk mitigation difficult. Current mitigation strategies tend to focus on changes to formulations, sourced materials, or manufacturing processes, which can be costly. Additionally, controlling the variables associated with N-nitrosamine formation is not always certain. Additional or alternative mitigation strategies need to be considered to fully address risk. This webinar will explore how new innovations in active material science technologies can be leveraged to deliver an active packaging-based solution that can react with NOx gases and nitrites in the packaging headspace to inhibit nitrosamine formation. These technologies can both stop nitrosamine formation and serve as an additional insurance policy by adsorbing/scavenging N-nitrosamines postformation to provide a holistic risk mitigation solution.

Key Learning Objectives:

• Explore the role nitrites in excipients play in nitrosamine formation
• Understand how mechanisms of reaction and root cause of nitrosamine formation inform mitigation strategies
• Learn how active material science scavenger technologies can meaningfully reduce nitrite impurity levels

Who Should Attend:

• Analytical scientists
• Formulation scientists
• Senior principal scientists/principal scientists
• Packaging directors
• Business development directors

Speakers:

Matt Riccio, MS
Director, Business Development
Aptar CSP Technologie

As director of business development at Aptar CSP Technology, Matthew Riccio, MS, leads nitrosamine mitigation business development efforts, staying abreast of regulatory guidance, collaborating with scientists, and serving as a key resource for scientific discussions on nitrosamine mitigation technologies. He has broad health care sector experience, particularly in medical device and injection products, and excels at identifying and capitalizing on emerging market opportunities. Riccio holds degrees in mechanical engineering and engineering management from Northeastern University in Boston, Massachusetts.


Jean Daou, PhD
R&D Manager
Aptar CSP Technologies

After earning a doctor of philosophy degree in material chemistry from the Université Louis Pasteur in Strasbourg, France, Jean Daou, PhD, joined the Université de Haute-Alsace in Mulhouse, France, as assistant professor and was promoted to full professor in 2016. In 2021, he joined Aptar CSP Technologies as R&D manager. His research activities focus on the synthesis of porous materials, the study of their properties and their shaping to meet pharmaceutical packaging demands for molecular decontamination. He is the author of 137 publications in international journals and holds 18 patents.

Jason D. Pratt, PhD, MS
Director, material Science
Aptar CSP Technologies

Jason D. Pratt, PhD, MS, is director of material science at Aptar CSP Technologies. An experienced scientist with a passion for innovative solutions to commercial opportunities, Pratt is skilled at bringing together and mentoring high-power teams to tackle impossible problems. He is a green chemist with over 40 patents across the food, cosmetics, pharma, and construction industries.

Register Free: https://www.pharmtech.com/pt_w/scavenger-technologies